MICHAEL K PITT Department of Statistics, University of Oxford, OX1 3TG and Nuffield College, Oxford, OX1 1NF, UK AND NEIL SHEPHARD Nuffield College, Oxford, OX1 1NF, UK JOINT AND ANTITHETIC MCMC FOR NON-GAUSSIAN MEASUREMENTS WITH APPLICATIONS TO STOCHASTIC VOLATILITY In this paper we examine methods for improving the efficiency of sampling the posterior distribution of the parameters of a non-Gaussian measurement models by simultaneously drawing the parameters and the states. We suggest that this is an effective strategy for reducing autocorrelation for MCMC\ methods. We also investigate the effect of attempting to induce negative correlation in the Metropolis chain by the use of antithetic variables. This is less successful in our experiments. The stochastic volatility model is considered as a motivating example throughout. KEYWORDS: Antithetic variables; Blocking; Kalman filter; Metropolis sampling; Non-Gaussian measurement models; Simulation smoother; Stochastic volatility.